Effects of Methadone Maintenance Treatment on Decision-Making Processes in Heroin-Abusers: A Cognitive Modeling Analysis

نویسندگان

  • Amir Dezfouli Center of Excellence for Control & Intelligent Processing Department of Electrical & Computer Engineering, Neuro Cognitive Laboratory, Iranian National Center for Addiction Studies,
  • Arash Khodadadi School of Electrical Engineering, Iran University of Science & Technology, Neuro Cognitive Laboratory, Iranian National Center for Addiction Studies,
  • Hamed Ekhtiari Neuro Cognitive Laboratory, Iranian National Center for Addiction Studies,
  • Pegah Fakhari Center of Excellence for Control & Intelligent Processing Department of Electrical & Computer Engineering,
چکیده مقاله:

A B S T R A C TIntroduction: Although decision-making processes have become a principal target of study among addiction researchers, few researches are published according to effects of different treatment methods on the cognitive processes underlying decision making up to now. Utilizing cognitive modeling method, in this paper we examine the effects of Methadone maintenance treatment (MMT) on cognitive processes underlying decision-making disorders in heroin-abusers. Methods: For this purpose, for the first time, we use the balloon analog risk task (BART) to assess the decision-making ability of heroin-abusers before and after treatment and compare it to the non heroin-dependent subjects. Results: Results demonstrate that heroin-abusers show more risky behavior than other groups. But, there is no difference between the performance of heroin-abusers after 6 months of MMT and control group. Modeling subjects’ behavior in BART reveals that poor performance in heroin-abusers is due to reward-dependency and insensitivity to evaluation. Discussion: Results show that 6 months of MMT decreases reward-dependency and increases sensitivity to evaluation.

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عنوان ژورنال

دوره 1  شماره 3

صفحات  44- 49

تاریخ انتشار 2010-05

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